| Taxing questions in development Trends in Microbiology, Volume 11, Issue 6, 1 June 2003, Pages 239-242 Judith P. Armitage Abstract Bacteria use taxis-controlled movement to reach their optimum environment. Chemotaxis is probably the best understood behavioural system in biology, biasing the normal random movement of bacteria using a phospho-relay pathway from receptors to the motility organelles. The pathways are typified by signal recognition and receptor adaptation, enabling bacteria to sense and respond to changing environments. Models have been derived from the single chemosensory pathway of but the sequencing of an increasing number of bacterial genomes is revealing genes that apparently encode multiple chemosensory pathways. Recently, data have accumulated suggesting that some of these pathways might not control motility, although the mechanisms by which this might happen remain unclear. Information from the soil bacterium could lead the way to an understanding of such mechanisms. Abstract | Full Text | PDF (104 kb) |
| Rhodobacter sphaeroides: complexity in chemotactic signalling Trends in Microbiology, Volume 16, Issue 6, 1 June 2008, Pages 251-260 Steven L. Porter, George H. Wadhams and Judith P. Armitage Abstract Most bacteria have much more complex chemosensory systems than those of the extensively studied . , for example, has multiple homologues of the chemosensory proteins. The roles of these homologues have been extensively investigated using a combination of deletion, subcellular localization and phosphorylation assays. These studies have shown that the homologues have specific roles in the sensory pathway, and they differ in their cellular localization and interactions with other components of the pathway. The presence of multiple chemosensory pathways might enable bacteria to tune their tactic responses to different environmental conditions. Abstract | Full Text | PDF (973 kb) |
| Function, Diversity, and Evolution of Signal Transduction in Prokaryotes Developmental Cell, Volume 4, Issue 4, 1 April 2003, Pages 459-465 Rasika M Harshey, Ikuro Kawagishi, Janine Maddock and Linda J Kenney Summary Major areas covered at the Bacterial Locomotion and Signal Transduction (BLAST) meeting included the clustering of chemoreceptors and its significance to signal amplification, organelle biogenesis, motility, developmental responses mediated by “chemotaxis” operons, and advances in two-component signaling mechanisms. Summary | Full Text | PDF (221 kb) |
Copyright © 2007 Elsevier Ltd. All rights reserved.
Current Biology, Volume 17, Issue 23, R1021-R1024, 4 December 2007
doi:10.1016/j.cub.2007.10.011
Dispatch
Melinda D. Baker2 and Jeffry B. Stock1, 2, 
1 Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA
2 Department of Chemistry, Princeton University, Princeton, New Jersey 98544, USA
Signal transduction systems that mediate adaptive changes in gene expression to specific sensory inputs have been well characterized. Recent studies have focused on mechanisms that allow crosstalk between different information-processing modalities.